A smiling female doctor in a white coat conducting an ultrasound exam on a patient lying on an examination table in a medical office. The patient appears relaxed while the doctor operates the ultrasound machine. This image represents the fertility workup

Fertility workup: What to expect and how to prepare

By Mindy Motta

|

This article may contain affiliate links, which means we may receive a small commission, at no cost to you, if you make a purchase through the link. We only recommend products we trust and believe will be beneficial to our readers.

If you've been trying to get pregnant without success, we know firsthand the emotional rollercoaster this journey can bring. The constant hope, the crushing disappointment, the endless Google searches for "best way to get pregnant" —it’s a lot. If you’re here, you might be wondering when to seek help and what a fertility workup entails.


First, let’s get the facts straight:

  • Infertility is defined as no successful pregnancy after one year of trying to conceive (if you’re under 35).

  • If you’re 35 or older, the timeframe shortens to six months without success.

If this sounds like you, don’t panic! A fertility workup is the next logical step, and while it can feel intimidating, it’s an empowering process that helps uncover potential reasons behind infertility and lays out a plan moving forward.


So, let’s break it down—what exactly happens during a fertility workup, what tests to expect, and how to best prepare for this next step. Plus, we’ll share some helpful products that can make the journey a little easier!



Step 1: Evaluating the fallopian tubes and uterus

Hysterosalpingogram (HSG) – Checking for blockages

A hysterosalpingogram (HSG) is an X-ray test that evaluates whether your fallopian tubes are open and if your uterus has any abnormalities that could interfere with pregnancy. During the test:

  • A contrast dye is inserted through your cervix.
  • X-rays are taken to watch the dye flow through your fallopian tubes.
  • If everything is clear, the dye will spill out at the ends of the tubes. If not, there may be a blockage.

Helpful tip

Some women report mild cramping during the procedure, so taking an over-the-counter pain reliever beforehand, like Advil Liquid Gels , can help ease discomfort.

Step 2: Checking your ovaries and uterus

Pelvic ultrasound – Monitoring ovarian function

A pelvic ultrasound is performed to:

  • Check your ovaries for follicle count (which can indicate ovarian reserve).
  • Monitor your uterus for fibroids, polyps, or other irregularities.

This is a transvaginal ultrasound procedure, and a full bladder is often needed, so be prepared to chug some water before your appointment!

Helpful tip

If you’re tracking ovulation, a basal body thermometer like the Easy@Home Smart Basal Thermometer can help you log temperature changes, which indicate when you’re ovulating.

Step 3: Blood work – A deep dive into your hormones

Your hormones play a key role in ovulation and pregnancy. Your doctor will order several blood tests to check for:

  • Thyroid function (TSH, T3, T4) – A healthy thyroid is critical for fertility.
  • Prolactin levels – High prolactin levels can disrupt ovulation.
  • Ovarian reserve (AMH Test) – Measures how many eggs you have left.
  • Ovulation hormones (FSH, LH, Progesterone, Estradiol) – Determines if you’re ovulating properly.
  • STI panel – Some sexually transmitted infections can impact fertility.

Additional blood work

Depending on your history, your doctor may also check:

  • Blood type & Rh factor – Important if blood incompatibility is a concern.
  • Rubella & varicella immunity – Ensures you’re protected from these infections during pregnancy.
  • HgA1c (Diabetes Test) – Uncontrolled blood sugar can impact fertility.
  • Recurrent pregnancy loss panel – If you’ve had three or more miscarriages , your doctor may order extra tests.

Step 4: Semen analysis – Checking his fertility too

Your partner isn’t off the hook! A semen analysis is a crucial part of the fertility workup. The test evaluates:

  • Sperm count: How many swimmers are in the pool?
  • Sperm shape (Morphology): Are they formed correctly?
  • Sperm motility: Can they move efficiently?

If the test shows any concerns, your doctor may recommend lifestyle changes or supplements like  Conception Men’s Fertility Supplement, which contain zinc and antioxidants to support healthy sperm.

Step 5: Next steps – Developing a fertility plan

Once all tests are complete, your doctor will help create a personalized fertility treatment plan . This may include:

  • Lifestyle changes – Adjusting diet, exercise, and stress management.
  • Medications – Clomid, Letrozole, or injectables to induce ovulation.
  • Surgery – If structural issues (like fibroids) are found.
  • Assisted Reproductive Technology (ART) – IUI or IVF, if needed.

How to prepare for a fertility workup

To get the most out of your appointment, come prepared!

What to bring

  • A detailed menstrual cycle history
  • A list of any medications or supplements you’re taking
  • Your partner’s health history (if applicable)
  • Any previous test results

Products to support the process

Final thoughts: Taking control of your fertility journey

A fertility workup can feel overwhelming, but it’s an empowering step in understanding your body and next steps for conception. Whether your journey leads to natural pregnancy, fertility treatments, or assisted reproductive options, knowledge is power .

Key takeaways

  • Don’t wait too long to seek help if you’re struggling to conceive.
  • A fertility workup is a roadmap —not a verdict. It helps you move forward.

The content on Awaiting the Stork™ is for informational purposes only and is not intended as medical advice, diagnosis, or treatment. Always consult with a qualified physician or healthcare professional to address your unique health needs and circumstances. 

Mindy Motta, FNP-C

Mindy is a seasoned OB-GYN Nurse Practitioner and co-founder of Awaiting the Stork™. After overcoming her own years-long fertility journey, she now blends clinical expertise with heartfelt empathy to offer new mom advice and evidence-based support for every stage of motherhood. Mindy’s mission is to nurture confidence, connection, and clarity for women stepping into motherhood’s many joys and challenges.

Related articles